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RECRUITINGPHASE2

Pan Tumor Rollover Study

Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.

Sponsor: Bristol-Myers SquibbEnrollment: 1500Conditions: Cancer
Huntsville, Alabama, United States | Tucson, Arizona, United States | Lynwood, California, United States +2 more
NCT03899155
RECRUITINGPHASE3

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

This phase III trial compares the effects of shorter chemotherapy (chemo)-immunotherapy without anthracyclines to usual chemo-immunotherapy for the treatment of early-stage triple negative breast cancer. Paclitaxel is in a class of medications called anti-microtubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be bette

Sponsor: SWOG Cancer Research NetworkEnrollment: 2400Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8
Birmingham, Alabama, United States | Anchorage, Alaska, United States | Anchorage, Alaska, United States +2 more
NCT05929768
RECRUITINGNA

Testing the Impact of the MOHR Follow-up Support

This study will evaluate the impact of 3 different strategies to increase engagement of participants in My Own Health Report (MOHR) and health behavior change activities over time. This study will evaluate the level of engagement, outcomes, cost and cost-effectiveness of these strategies.

Sponsor: University of Colorado, DenverEnrollment: 1000Conditions: Implementation Strategy Bundles for Structured Follow-up
Aurora, Colorado, United States | Denver, Colorado, United States | Denver, Colorado, United States +2 more
NCT07569224
RECRUITINGNA

Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants

Sponsor: Senthil SadhasivamEnrollment: 700Conditions: Cesarean Section Complications, Opioid Use
Indianapolis, Indiana, United States | St Louis, Missouri, United States | Pittsburgh, Pennsylvania, United States +1 more
NCT05380531
RECRUITINGNA

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

The goal of this clinical trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with uncomplicated type B aortic dissection.

Sponsor: Duke UniversityEnrollment: 1100Conditions: Type B Aortic Dissection
Birmingham, Alabama, United States | Phoenix, Arizona, United States | Long Beach, California, United States +2 more
NCT06087029

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